Search results for "bisphénol a"

showing 4 items of 4 documents

Regulatory identification of BPA as an endocrine disruptor : Context and methodology

2018

International audience; BPA is one of the most investigated substances for its endocrine disruptor (ED) properties and it is at the same time in the center of many ED-related controversies, the analysis on how BPA fits to the regulatory identification as an ED is a challenge in terms of methodology. It is also a great opportunity to test the regulatory framework with a uniquely data-rich substance and learn valuable lessons for future cases. From this extensive database, it was considered important to engage in a detailed analysis so as to provide specific and strong evidences of ED while reflecting accurately the complexity of the response as well the multiplicity of adverse effects. An ap…

0301 basic medicineendocrine systemBrain developmentpertubateur endocrinienEndocrine disruptionContext (language use)Computational biologyMESH: Social Control Formal010501 environmental sciencesBiologyEndocrine Disruptors01 natural sciencesBiochemistryMammary gland developmentbisphenol A;endocrine disruption;ED;SVHC;substance of very high concern;REACh03 medical and health sciencesEndocrinologyBisphenol AMESH: PhenolsPhenolsSubstance of very high concernMESH: Benzhydryl CompoundsFood and Nutritionbisphénol aAnimalsHumansBenzhydryl CompoundsMolecular BiologyComputingMilieux_MISCELLANEOUSSVHC0105 earth and related environmental sciencesEndocrinology and metabolismurogenital systemsubstance toxiqueED3. Good healthSocial Control FormalMESH: Endocrine Disruptors030104 developmental biologyEndocrine disruptor[SDV.TOX]Life Sciences [q-bio]/ToxicologyAlimentation et NutritionEndocrinologie et métabolismeREACHIdentification (biology)
researchProduct

BPA, an Energy Balance Disruptor

2014

International audience; Bisphenol A (BPA) is used extensively in the world and is present in a diverse range of manufactured articles including dental resins, polycarbonate plastics, and the inner coating of food cans. It is a high volume chemical, with global production at 3.6 × 109 kg per year. BPA was identified as a high priority for assessment of human health risk because it was considered to present greatest potential for human exposure. Most studies of the health effects of BPA have focused on endocrine disruption leading to reproductive toxicity, but it displays additional side effects, including liver damage, disrupted pancreatic β-cell function, thyroid hormone disruption, and obe…

Malemedicine.medical_specialtyBisphenol Aendocrine systemDental resins[SDV]Life Sciences [q-bio]Energy balanceEndocrine Disruptors010501 environmental sciencesWeight Gain01 natural sciencesIndustrial and Manufacturing Engineering03 medical and health sciencesHuman healthchemistry.chemical_compoundPhenolsInternal medicinemedicineAnimalsHumansLiver damageBenzhydryl Compounds030304 developmental biology0105 earth and related environmental sciences0303 health sciencesurogenital systemEnvironmental ExposureGeneral MedicineBisphénol ABPARats3. Good healthEndocrinologychemistryEndocrine disruptorHuman exposureFemale[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieEnergy MetabolismReproductive toxicityFood Science
researchProduct

Analyse critique des résultats d’une étude de toxicité sur le développement du système nerveux ainsi que d’autres données publiées récemment sur les …

2010

Rapport d’expertise collective AFSSA; Analyse critique des résultats d’une étude de toxicité sur le développement du système nerveux ainsi que d’autres données publiées récemment sur les effets toxiques du bisphénol A

perturbateur endocrinien[SDV.OT]Life Sciences [q-bio]/Other [q-bio.OT]rapport d'expertise[SDV.OT] Life Sciences [q-bio]/Other [q-bio.OT][ SDV.AEN ] Life Sciences [q-bio]/Food and Nutrition[ SDV.TOX ] Life Sciences [q-bio]/Toxicologysignaux d'alerteBisphénol A[SDV.TOX] Life Sciences [q-bio]/Toxicology[SDV.AEN] Life Sciences [q-bio]/Food and Nutritionfenêtre d'exposition[SDV.TOX]Life Sciences [q-bio]/Toxicologytoxicité[ SDV.OT ] Life Sciences [q-bio]/Other [q-bio.OT]système nerveux[SDV.AEN]Life Sciences [q-bio]/Food and Nutritiondéveloppement
researchProduct

Exposition continue à des mélanges de perturbateurs endocriniens

2012

Dans ce projet, il est question d’explorer les effets de mélanges de perturbateurs endocriniens sur plusieurs générations, en considérant des cibles différentes (appareil reproducteur, glande mammaire, os, dent, tissu adipeux, glandes salivaires, cerveau...) et adaptées à chaque âge pour essayer de mieux comprendre comment agissent des perturbateurs endocriniens, en particulier ceux qui interfèrent avec les hormones sexuelles. Parmi les questions majeures que se pose le scientifique, figurent celles de l’effet d’une exposition prolongée à des mélanges de perturbateurs endocriniens depuis la conception jusqu’à l’âge adulte, et de la possibilité que ces expositions aient des répercussions sur…

perturbateur endocrinienreproduction[SDV] Life Sciences [q-bio]génistéinedose effetbisphénol A[SDV.EE.SANT] Life Sciences [q-bio]/Ecology environment/Healthmécanisme actioncellulefaible doseexposition
researchProduct